Functional imaging -- schizophrenia
نویسندگان
چکیده
منابع مشابه
Functional magnetic resonance imaging in schizophrenia
The integration of functional magnetic resonance imaging (fMRI) with cognitive and affective neuroscience paradigms enables examination of the brain systems underlying the behavioral deficits manifested in schizophrenia; there have been a remarkable increase in the number of studies that apply fMRI in neurobiological studies of this disease. This article summarizes features of fMRI methodology ...
متن کاملFunctional and anatomical brain imaging: impact on schizophrenia research.
A group of related new technologies has made it possible to study the brain's regional changes in metabolism, blood flow, electrical activity, and neurochemistry. Positron emission tomography (PET) produces slice images of radioisotope density--brain metabolism or receptor concentration can be quantitated. Studies in schizophrenia have indicated relative metabolic underactivity of the frontal l...
متن کاملMapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging.
BACKGROUND Perceptions of speech in the absence of an auditory stimulus (auditory verbal hallucinations) are a cardinal feature of schizophrenia. Functional neuroimaging provides a powerful means of measuring neural activity during auditory hallucinations, but the results from previous studies have been inconsistent. This may reflect the acquisition of small numbers of images in each subject an...
متن کاملConvergent Approaches for Defining Functional Imaging Endophenotypes in Schizophrenia
In complex genetic disorders such as schizophrenia, endophenotypes have potential utility both in identifying risk genes and in illuminating pathophysiology. This is due to their presumed status as closer in the etiopathological pathway to the causative genes than is the currently defining clinical phenomenology of the illness and thus their simpler genetic architecture than that of the full sy...
متن کاملProcedural learning in schizophrenia investigated with functional magnetic resonance imaging.
A cerebral basis for the acquisition and retention of procedural knowledge in schizophrenia was examined with 1.5 T functional MRI during an embedded sequence Serial Reaction Time Task (SRTT) in 10 chronic medicated patients and 15 healthy controls. Comparable procedural learning was observed in both groups, suggesting that the impairment reported in previous schizophrenia samples may not be ro...
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ژورنال
عنوان ژورنال: British Medical Bulletin
سال: 1996
ISSN: 0007-1420,1471-8391
DOI: 10.1093/oxfordjournals.bmb.a011562